Some synthetic refrigerants which were often used in the past have been severely restricted by the F-Gas Regulation. Nevertheless, these refrigerants are still used in many areas, in compliance with the applicable standards and laws. Currently there are many usable options, even with a low GWP. These refrigerants, partly due to their mixture components, fall under a flammability class A2L, which entails specific safety regulations. Due to the changes on the refrigerant market, more and more components are being developed for the new mixtures and are finding their way into our systems.